CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4323
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 1-[4-[(1S)-1-amino-2-oxo-2-(1,3-thiazolidin-3-yl)ethyl]cyclohexyl]-3-(4-iodophenyl)urea family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00355112 Functional Category Bioactive with Natural Product
Superfamily Cathepsin L1 and Stromelysin-1 Binder Superfamily
Class Class 3354

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor Su... 1 1
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 1
Prothrombin and Trypsin-1 inhibitor N-[4-[(diaminomethylidenea... 1 6
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00355112 CHEMBL140350 Bioactive 1-[4-[(1S)-1-amino-2-oxo-2-(1,3-thiazolidin-3-yl)ethyl]cyclohexyl]-3-(4-iodophenyl)urea
CFAMM00355110 CHEMBL143590 Bioactive 3-[4-[[4-[(1S)-1-amino-2-oxo-2-(1,3-thiazolidin-3-yl)ethyl]cyclohexyl]sulfamoyl]phenyl]-1,1-dimethylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

85539 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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