CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43415
Family Name Metabotropic glutamate receptor 5 ligand AGN-PC-075XWO family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00521664 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Mitogen-activated protein kinase 10 Inhibitor AS-601245 Superfamily
Class Class 2477

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Metabotropic glutamate receptor 5 Ligand 4-(4-chlorophenylthio... 4 17
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
D(2) dopamine receptor Ligand PD-135146 Family 5 11
Reverse transcriptase Inhibitor HI-443 Family 1 0
Nuclear receptor ROR-gamma and Lysine-specific demethylase 4E ... 1 0
Nitric oxide synthase, brain inhibitor SureCN1387416 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00521665 CHEMBL85997 Bioactive AGN-PC-00FY7Z
CFAMM00521664 CHEMBL198305 Bioactive AGN-PC-075XWO

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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