CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4360
Family Name Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)phenoxy]phenyl]sulfonyl-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00355397 Functional Category Bioactive
Superfamily Neutrophil collagenase and Stromelysin-1 Binder Superfamily
Class Class 3978

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Oxytocin receptor and Vasopressin V1a receptor ligand N-(4-chl... 9 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 12
Pol polyprotein inhibitor AC1LAGJO family 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073U... 4 6
Neutrophil collagenase and Stromelysin-1 inhibitor tert-butyl ... 2 0
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 2 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 1
Stromelysin-1 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 26 12
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(1-cyanocyclop... 4 0
Bone morphogenetic protein 1 inhibitor 3-[[4-(benzylcarbamoyla... 1 9
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 20 23
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 4 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 3-N-hyd... 1 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
Somatostatin receptor type 1 ligand AGN-PC-078XQK family 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(3S)-2... 2 2
Coagulation factor X inhibitor N-[1-[2-fluoro-4-(2-methylsulfo... 2 2
Elongation of very long chain fatty acids protein 6 inhibitor ... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00355397 CHEMBL292226 Bioactive (3R)-2-[4-[4-(dimethylamino)phenoxy]phenyl]sulfonyl-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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