CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43611
Family Name Sodium channel protein type 9 subunit alpha and Sodium channel protein type 5 subunit alpha ligand 2-N-[4-[4-(trifluoromethoxy)phenoxy]phenyl]pyrazine-2,6-diamine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00521968 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Binder Superfamily 2
Class Class 153

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mepyramine Family 5 65
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
SB1518 family 7 103
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Lethal factor and Dual specificity protein kinase CLK4 inhibit... 1 3
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Huntingtin and Nuclear receptor ROR-gamma ligand CHEMBL1324975... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00521969 CHEMBL2012044 Bioactive 2-N-[4-[4-(trifluoromethyl)phenoxy]phenyl]pyrazine-2,6-diamine
CFAMM00521968 CHEMBL2010816 Bioactive 2-N-[4-[4-(trifluoromethoxy)phenoxy]phenyl]pyrazine-2,6-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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