CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4363
Family Name Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073UA0 family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00260921 Functional Category Bioactive
Superfamily Macrophage metalloelastase Inhibitor PF-00356231 Superfamily
Class Class 1827

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(1-methylin... 4 1
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Coagulation factor X and Prothrombin inhibitor SureCN8237487 f... 16 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Coagulation factor X and Anionic trypsin inhibitor Sulfonamido... 2 4
Calpain-1 catalytic subunit inhibitor (3S)-3-[[(2R)-2-(methane... 1 0
Interstitial collagenase and Stromelysin-1 inhibitor 2-[ethoxy... 1 1
Calpain-1 catalytic subunit inhibitor 2,5-dichloro-N-[(2S)-3,4... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00355417 CHEMBL344633 Bioactive (3S)-N-hydroxy-2,2-dimethyl-4-(5-pyridin-2-ylthiophen-2-yl)sulfonyl-1,4-thiazepane-3-carboxamide
CFAMM00355421 CHEMBL56909 Bioactive (3R)-N-hydroxy-2-[(5-pyridin-2-ylthiophen-2-yl)methylsulfonyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43937 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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