CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4382
Family Name Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhibitor (2S)-N-hydroxy-2-[2-methylpropyl-(4-phenylphenyl)sulfonylamino]-4-methylsulfanylbutanamide family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00279471 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Secreted frizzled-related protein 1 Binder Superfamily
Class Class 4047

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Stromelysin-1 Inhibitor PD-1694... 10 10
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 8 4
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Interstitial collagenase and Collagenase 3 inhibitor (3S)-4-(4... 4 1
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
72 kDa type IV collagenase and Matrix metalloproteinase-14 inh... 1 0
Neutrophil collagenase and Collagenase 3 inhibitor (2R)-2-[2-a... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Microbial collagenase inhibitor AGN-PC-00F1J7 family 4 2
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-2-... 2 0
Endothelin-converting enzyme 1 and Angiotensin-converting enzy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00355555 CHEMBL344634 Bioactive (3S)-4-[4-(4-fluorophenyl)phenyl]sulfonyl-N-hydroxy-2,2-dimethyl-1,4-thiazepane-3-carboxamide
CFAMM00355554 CHEMBL343082 Bioactive (3S)-N-hydroxy-2,2-dimethyl-4-(4-pentylphenyl)sulfonyl-1,4-thiazepane-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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