CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43821
Family Name Prostaglandin E synthase inhibitor 2-chloro-N-[3-[[4-(3-chlorophenyl)phenyl]methyl]-4-oxo-2-propylquinazolin-6-yl]benzamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00522554 Functional Category Bioactive
Superfamily Prostaglandin E synthase Binder Superfamily 5
Class Class 4685

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3
Telomerase reverse transcriptase inhibitor AGN-PC-07ZBGW family 2 0


External ID

Functional Category

Molecule Name

CFAMM00522551 CHEMBL2046480 Bioactive 2-chloro-N-[4-oxo-3-[(4-phenylphenyl)methyl]-2-propylquinazolin-6-yl]benzamide
CFAMM00522550 CHEMBL2049148 Bioactive 2-chloro-N-[3-[[4-(4-chlorophenyl)phenyl]methyl]-4-oxo-2-propylquinazolin-6-yl]benzamide
CFAMM00522554 CHEMBL571026 Bioactive 2-chloro-N-[3-[[4-(3-chlorophenyl)phenyl]methyl]-4-oxo-2-propylquinazolin-6-yl]benzamide
CFAMM00522553 CHEMBL2046486 Bioactive N-[3-[(3-chlorophenyl)methyl]-4-oxo-2-propylquinazolin-6-yl]-2-methylbenzamide
CFAMM00522552 CHEMBL2046481 Bioactive 2-chloro-N-[3-[(3-chlorophenyl)methyl]-4-oxo-2-propylquinazolin-6-yl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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