CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43927
Family Name Cytochrome P450 1A1 and Cytochrome P450 1B1 inhibitor 1,2,4-trimethoxy-5-[(E)-2-(4-methylsulfanylphenyl)ethenyl]benzene family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00522738 Functional Category Bioactive
Superfamily Cytochrome P450 1B1 and Cytochrome P450 1A1 Binder Superfamily
Class Class 1980

Cousin Family NamesSeedsMembers
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Cytochrome P450 1B1 Inhibitor 2-[2-(3,5-dimethoxy-phenyl)-viny... 2 2
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00522738 CHEMBL2071351 Bioactive 1,2,4-trimethoxy-5-[(E)-2-(4-methylsulfanylphenyl)ethenyl]benzene

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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