CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44036
Family Name Pol polyprotein inhibitor methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[(1S)-1-[[(2S)-2-aminopropanoyl]amino]ethyl]-3-benzyl-2,3,6,7-tetrahydroazepin-1-yl]propanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoate family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00523034 Functional Category Bioactive
Superfamily Pol polyprotein and Thyrotropin receptor Binder Superfamily
Class Class 260

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Prothrombin Inhibitor Efegatran Family 9 47
Neprilysin Inhibitor Thiorphan Family 41 68
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenylo... 2 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Tryptase alpha/beta-1 inhibitor methyl 3-[3-(aminomethyl)pheny... 1 3
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 6
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Transcriptional activator protein LuxR inhibitor 3-(3-iodophen... 8 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00523034 CHEMBL2115172 Bioactive methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[(1S)-1-[[(2S)-2-aminopropanoyl]amino]ethyl]-3-benzyl-2,3,6,7-tetrahydroazepin-1-yl]propanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543