CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44090
Family Name Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoyl)naphthalen-2-yl]oxybut-2-enamide family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00523149 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase Inhibitor Taspine Superfamily
Class Class 2572

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Melanin-concentrating hormone receptor 1 and Potassium voltage... 12 53
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Arachidonate 5-lipoxygenase inhibitor 1-hydroxy-1-[1-[2-(3,4,5... 2 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor (E)-6-(4-hy... 1 10
Cholesteryl ester transfer protein inhibitor [8-[(1S)-1-hydrox... 4 10
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Calpain-1 catalytic subunit inhibitor (3S)-3-[[4-[2-(methoxyme... 2 4
Putative NP ZINC08790414 Family 23 0
NP 2-(5,7-dihydroxy-4-methyl-2-oxo-2h-chromen-3-yl)-n-(3-(fura... 6 0
NP (z)-2-(4-isopropylbenzylidene)-3-oxo-2,3-dihydrobenzofuran-... 16 0
Putative NP ZINC02127056 Family 4 1
Putative NP ZINC08790868 Family 10 0
Putative NP ZINC02124510 Family 1 0
NP 2-((5-hydroxy-2,2-dimethyl-4-oxochroman-7-yl)oxy)-n-(3-meth... 18 0
Putative NP ZINC04085259 Family 3 0
NP 2-((1'-acetyl-4-oxospiro[chroman-2,4'-piperidin]-7-yl)oxy)-... 5 0
NP 5-hydroxy-4-oxo-2-phenyl-4h-chromen-7-yl 2-((tert-butoxycar... 19 0
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0
NP 7-(2-((4as,8as)-4a-hydroxyoctahydroisoquinolin-2(1h)-yl)-2-... 3 0
hydroxyspiro[3H-chromene-2,4'-piperidine]-4-one NP 1'-acetyl-7... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00523149 CHEMBL214974 Bioactive (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoyl)naphthalen-2-yl]oxybut-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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