CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44221
Family Name Hypoxia-inducible factor 1-alpha inhibitor 2-morpholin-4-ylethyl 3-[[(E)-3-[4-(1-adamantyl)phenoxy]prop-2-enoyl]amino]benzoate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00523410 Functional Category Bioactive
Superfamily Prelamin-A/C and Kappa-type opioid receptor Binder Superfamily
Class Class 1203

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Leukotriene A-4 hydrolase inhibitor AGN-PC-0A9QDC family 2 5
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Follicle-stimulating hormone receptor ligand (1-acetyl-2,2,4-t... 1 2


External ID

Functional Category

Molecule Name

CFAMM00523411 CHEMBL567798 Bioactive AGN-PC-07CRDR
CFAMM00523410 CHEMBL2178399 Bioactive 2-morpholin-4-ylethyl 3-[[(E)-3-[4-(1-adamantyl)phenoxy]prop-2-enoyl]amino]benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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