CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44232
Family Name Cellular tumor antigen p53 and E3 ubiquitin-protein ligase Mdm2 inhibitor AC1NXXNY family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00523428 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Aromatase Binder Superfamily
Class Class 794

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Aromatase Inhibitor 2-(1h-imidazol-1-yl)-1-(4-nitrophenyl)etha... 2 29
Thromboxane-A synthase Inhibitor 2-(6-imidazol-1-yl-hexyl)-iso... 3 6
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7


External ID

Functional Category

Molecule Name

CFAMM00523428 CHEMBL2180103 Bioactive AC1NXXNY
CFAMM00523427 CHEMBL2180110 Bioactive AC1NXXNS
CFAMM00523429 CHEMBL2180107 Bioactive (4Z)-4-[hydroxy(phenyl)methylidene]-1-(3-imidazol-1-ylpropyl)-5-[4-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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