CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4428
Family Name Prelamin-A/C and Solute carrier organic anion transporter family member 1B1 inhibitor Nonoxynol 9 family
No. of Seeds 1 No. of Other Members 15
Family Centroid CFAMM00355954 Functional Category Bioactive
Superfamily Prelamin-A/C and Cytochrome P450 2C9 Binder Superfamily 2
Class Class 426

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand Dienestrol Family 35 440
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Salicin family 5 629
Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Glucokinase Inhibitor R7201 Family 22 105
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
TS-071 family 8 36
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Tubulin beta chain Inhibitor Combretastatin Family 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene ... 3 85
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin D2 receptor 2 Ligand 2-(4-cyano-2-cyclohexylphen... 6 3
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Androgen receptor Ligand 3-methoxy-4-(m-tolyloxy)benzonitrile ... 3 29
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Aromatase Inhibitor NSC-122427 Family 1 0
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Histone deacetylase 2 and Histone deacetylase 8 inhibitor 2-hy... 1 0
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
Beta-lactamase inhibitor AGN-PC-0A9UJZ family 1 3
Cannabinoid receptor 1 and Monoglyceride lipase ligand 4-(4-ph... 4 4
Acetylcholinesterase inhibitor (2R,3S,4S,5R,6S)-2-(hydroxymeth... 1 1
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0
3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole NP (3ar,5r,6s,6ar)... 18 6
NP (r)-(2-(4-isopropoxybenzyl)-4-methyl-4,5-dihydrooxazol-4-yl... 3 0
ahydropyrano[3,2-c]chromene NP ZINC04023039 Family 16 2
3-(2,3-dihydro-1,4-benzodioxin-6-yl)chromene-4-thione NP 3-(2,... 1 0
2-(4-methoxyphenyl)-10,10-dimethyl-1,3,9-trioxaspiro[5.5]undec... 4 19


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00355954 CHEMBL1410 Bioactive Nonoxynol 9

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27052 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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