CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4430
Family Name Neutrophil collagenase and Stromelysin-1 inhibitor tert-butyl (3S)-4-[[3-(hydroxycarbamoyl)-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-7-yl]amino]-4-oxo-3-[(2-phenylacetyl)amino]butanoate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00352699 Functional Category Bioactive
Superfamily Neutrophil collagenase and Stromelysin-1 Binder Superfamily
Class Class 3978

Cousin Family NamesSeedsMembers
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Pol polyprotein inhibitor AC1LAPRV family 13 7
Pol polyprotein inhibitor AC1LAGJO family 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)p... 2 4
Pol polyprotein inhibitor SureCN4637317 family 19 6
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
Coagulation factor X inhibitor N-[1-[2-fluoro-4-(2-methylsulfo... 2 2


External ID

Functional Category

Molecule Name

CFAMM00355978 CHEMBL262264 Bioactive tert-butyl (3S)-4-[[(3S)-3-(hydroxycarbamoyl)-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-7-yl]amino]-4-oxo-3-(phenylmethoxycarbonylamino)butanoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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