CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44332
Family Name Sigma non-opioid intracellular receptor 1 ligand methyl 1-(4-chlorophenyl)-2-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]cyclopropane-1-carboxylate family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00523614 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 Binder Superfamily 11
Class Class 898

Cousin Family NamesSeedsMembers
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0


External ID

Functional Category

Molecule Name

CFAMM00523615 CHEMBL222307 Bioactive methyl 1-(4-chlorophenyl)-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]cyclopropane-1-carboxylate
CFAMM00523614 CHEMBL221347 Bioactive methyl 1-(4-chlorophenyl)-2-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]cyclopropane-1-carboxylate
CFAMM00523617 CHEMBL222394 Bioactive methyl 1-(4-methylphenyl)-2-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]cyclopropane-1-carboxylate
CFAMM00523616 CHEMBL386002 Bioactive methyl 1-(4-methylphenyl)-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]cyclopropane-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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