CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM444
Family Name Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-PC-04YYC4 family
No. of Seeds 7 No. of Other Members 19
Family Centroid CFAMM00042477 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Ripazepam Superfamily
Class Class 843

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
HIV protease Inhibitor BIT225 Family 2 2
Kinase and DNAPKi Inhibitor CC-115 Family 1 1
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Melanocortin receptor 4 and Melanocortin receptor 3 ligand N-[... 1 0
P2X purinoceptor 7 inhibitor N-[(2-chloro-3,4-difluorophenyl)m... 6 64
P2X purinoceptor 7 inhibitor N-[[2-chloro-3-(trifluoromethyl)p... 3 10
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
5-hydroxytryptamine receptor 3A ligand N-[(1S,5S)-9-methyl-9-a... 1 0
5-hydroxytryptamine receptor 3A ligand 1-[3-[[5-(dimethylamino... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Lysosomal Pro-X carboxypeptidase inhibitor [(1R,2R,4S)-4-amino... 9 0
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
5-hydroxytryptamine receptor 4 ligand N-[(1R,5S)-8-[2-hydroxy-... 4 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 2 1
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 1 0
5-hydroxytryptamine receptor 3A ligand 5-hydroxy-1-methyl-N-[(... 4 2
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (2... 5 5
Mitogen-activated protein kinase 8 inhibitor 5-[(6-chloro-1-ox... 5 7
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-(3-methyl-6,7-... 6 1
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-[3-(4-chloroph... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor py... 1 3
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6
P2X purinoceptor 7 inhibitor AGN-PC-0C7PCI family 1 10
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311604 CHEMBL461773 Bioactive SureCN3144319

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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