CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4445
Family Name Neutrophil elastase inhibitor SureCN7423499 family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00356146 Functional Category Bioactive
Superfamily Neutrophil elastase and C-C chemokine receptor type 5 Binder Superfamily
Class Class 3296

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Neutrophil elastase Inhibitor FK-706 Family 8 85
Alpha-1A adrenergic receptor Ligand SNAP-6201 Family 41 94
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
Neutrophil elastase inhibitor 2-[3-(benzylsulfamoylamino)-2-ox... 5 27
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Cannabinoid receptor 2 ligand AGN-PC-087MPO family 7 21
Dipeptidyl peptidase 4 inhibitor SureCN389715 family 2 2
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 9 21
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Gonadotropin-releasing hormone receptor and Cytochrome P450 3A... 7 8
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 20 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00356142 CHEMBL276307 Bioactive SureCN7423197
CFAMM00356141 CHEMBL275340 Bioactive 2-[3-[2-(benzylamino)-2-oxoethyl]-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide
CFAMM00356140 CHEMBL14165 Bioactive 2-[3-(2-ethoxyethyl)-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide
CFAMM00356146 CHEMBL14115 Bioactive SureCN7423499
CFAMM00356144 CHEMBL14293 Bioactive 2-[3-(2-morpholin-4-ylethyl)-2,4,8-trioxo-6-phenyl-1H-pyrido[3,4-d]pyrimidin-7-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27161 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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