CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44554
Family Name Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 inhibitor (E)-1-(4-chloropiperidin-1-yl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-en-1-one family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00524087 Functional Category Bioactive with Natural Product
Superfamily Cytochrome P450 3A4 and Cellular tumor antigen p53 Binder Superfamily 2
Class Class 1241

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Tubulin beta chain Inhibitor Colchinol Family 3 109
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 191
Cytochrome P450 3A4 and Cellular tumor antigen p53 inhibitor P... 1 7


External ID

Functional Category

Molecule Name

CFAMM00524084 CHEMBL2333743 Bioactive (E)-N-(3-chloropropyl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
CFAMM00524083 CHEMBL2333742 Bioactive (E)-N-(2-chloroethyl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
CFAMM00524089 CHEMBL2333738 Bioactive (E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-morpholin-4-ylprop-2-en-1-one
CFAMM00524088 CHEMBL2333733 Bioactive (E)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(3,5-dimethylpiperidin-1-yl)prop-2-en-1-one
CFAMM00524087 CHEMBL2333735 Bioactive (E)-1-(4-chloropiperidin-1-yl)-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-en-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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