CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44733
Family Name Histamine H4 receptor ligand 4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]pyrimidine-2,4-diamine family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00524518 Functional Category Bioactive
Superfamily Cathepsin K Inhibitor 4-cyclohexylamino-pyrimidine-2-carbonitrile Superfamily
Class Class 2378

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor 4-cyclohexylamino-pyrimidine-2-carbonitr... 2 3
Oestrogen receptor Ligand N,n,n-triisobutyl-pyrimidine-2,4,6-t... 13 58
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 4 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 3
DNA-(apurinic or apyrimidinic site) lyase and Caspase-7 inhibi... 1 1
Diazines Metabolite Pyrimidine Family 2 12


External ID

Functional Category

Molecule Name

CFAMM00524518 CHEMBL2375754 Bioactive 4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]pyrimidine-2,4-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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