CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44806
Family Name 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor ligand 7-[4-[4-(4-fluorobenzoyl)piperidin-1-yl]butoxy]-4-methylchromen-2-one family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00524678 Functional Category Bioactive with Natural Product
Superfamily Sodium channel protein type 5 subunit alpha Ligand Dyclonine Superfamily
Class Class 298

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Ipriflavone family 62 2480
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Acolbifene family 10 115
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Acetylcholinesterase Inhibitor AP-2238 Family 2 109
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Disintegrin and metalloproteinase domain-containing protein 17... 9 2
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(... 5 2
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 1 65
Estrogen receptor ligand AGN-PC-073KIM family 1 0
Amine oxidase [flavin-containing] B inhibitor (2S)-1-[[7-[(3-f... 2 15
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R9XR fa... 1 7
Platelet-activating factor receptor ligand Oprea1_769373 family 2 0
Putative NP ZINC00174842 Family 4 0
hydroxyspiro[3H-chromene-2,4'-piperidine]-4-one NP 1'-acetyl-7... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00524678 CHEMBL2387251 Bioactive 7-[4-[4-(4-fluorobenzoyl)piperidin-1-yl]butoxy]-4-methylchromen-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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