CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44862
Family Name Serine/threonine-protein kinase pim-3 and Serine/threonine-protein kinase pim-1 inhibitor 9-methoxy-5-nitro-2,3-dihydropyrazolo[3,4-c]carbazole family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00524869 Functional Category Bioactive with Natural Product
Superfamily Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-3 Binder Superfamily 4
Class Class 5849

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 9 1
Acetylcholinesterase and Cholinesterase inhibitor P10358 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00524864 CHEMBL2397599 Bioactive 9-methoxy-5-nitro-1,2-dihydropyrazolo[4,3-c]carbazole
CFAMM00524872 CHEMBL2397521 Bioactive 9-methoxy-1,2-dihydropyrazolo[4,3-c]carbazol-5-amine
CFAMM00524869 CHEMBL2397524 Bioactive 9-methoxy-5-nitro-2,3-dihydropyrazolo[3,4-c]carbazole
CFAMM00524868 CHEMBL2397527 Bioactive 9-methoxy-2,3-dihydropyrazolo[3,4-c]carbazol-5-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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