CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44937
Family Name Histone deacetylase 6 and Histone deacetylase 1 inhibitor (E)-3-[5-[[benzyl(ethyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00525079 Functional Category Bioactive
Superfamily Survival motor neuron protein and Huntingtin Binder Superfamily
Class Class 2912

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
Cytochrome P450 2D6 Inhibitor (5-phenylfuran-2-yl)methanamine ... 1 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 10
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6


External ID

Functional Category

Molecule Name

CFAMM00525079 CHEMBL2413316 Bioactive (E)-3-[5-[[benzyl(ethyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
CFAMM00525078 CHEMBL2413319 Bioactive (E)-3-[5-[[benzyl(butyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
CFAMM00525077 CHEMBL2413292 Bioactive (E)-3-[5-[[benzyl(2-hydroxyethyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide
CFAMM00525080 CHEMBL2413317 Bioactive (E)-3-[5-[[benzyl(propyl)amino]methyl]furan-2-yl]-N-hydroxyprop-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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