CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44944
Family Name Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymerase 1 inhibitor 5-amino-3-(4-chlorophenyl)-2H-isoquinolin-1-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00525098 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymerase 1 inhibitor 5-amino-3-(4-chlorophenyl)-2H-isoquinolin-1-one Superfamily
Class Class 6894

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Phospholipase D1 Inhibitor Halopemide Family 17 111
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 i... 1 0
G protein-activated inward rectifier potassium channel 4 and G... 1 0
1-benzoyl-6-chloro-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00525098 CHEMBL2414046 Bioactive 5-amino-3-(4-chlorophenyl)-2H-isoquinolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27276 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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