CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44973
Family Name Malate dehydrogenase, mitochondrial and Lactate dehydrogenase inhibitor Oxamic acid derivative, 7 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00525147 Functional Category Bioactive
Superfamily Tyrosine-protein phosphatase non-receptor type 1 Ligand Oxalylaminobenzoic Acid Superfamily
Class Class 2714

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand R... 1 16
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Pol polyprotein inhibitor AC1LA3B0 family 1 2
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Hepatocyte growth factor receptor ligand 2-[(2-fluorophenyl)me... 6 11
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransfer... 1 0
Nuclear receptor ROR-gamma and Retinal dehydrogenase 1 ligand ... 1 8
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Tyrosine-protein kinase ABL1 inhibitor N-(4-bromophenyl)-2-(5-... 1 3
Urokinase-type plasminogen activator and Tissue-type plasminog... 1 0


External ID

Functional Category

Molecule Name

CFAMM00525147 CHEMBL242020 Bioactive Oxamic acid derivative, 7

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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