CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM44987
Family Name G protein-activated inward rectifier potassium channel 4 and G protein-activated inward rectifier potassium channel 1 ligand 2-(2-chlorophenyl)-N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00525170 Functional Category Bioactive
Superfamily Cruzipain and Bifunctional epoxide hydrolase 2 Binder Superfamily
Class Class 564

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Pan-DAC Inhibitor AR-42 Family 21 153
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Transient receptor potential cation channel subfamily V member... 1 5
Phospholipase D1 Inhibitor Halopemide Family 17 111
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Cruzipain Inhibitor N1,n4-bis(5-chloro-2-methylphenyl)succinam... 1 5
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00525170 CHEMBL2420532 Bioactive 2-(2-chlorophenyl)-N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543