CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45176
Family Name Sodium channel protein type 9 subunit alpha and Sodium channel protein type 10 subunit alpha ligand tert-butyl N-[(2R)-3-(2-chloro-5-fluorophenyl)-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00525513 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Bile acid receptor Binder Superfamily
Class Class 181

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2


External ID

Functional Category

Molecule Name

CFAMM00525508 CHEMBL400845 Bioactive tert-butyl N-[(2R)-3-(2-chloro-6-fluorophenyl)-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate
CFAMM00525514 CHEMBL404623 Bioactive tert-butyl N-[(2R)-3-[4-fluoro-2-(trifluoromethyl)phenyl]-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate
CFAMM00525513 CHEMBL252837 Bioactive tert-butyl N-[(2R)-3-(2-chloro-5-fluorophenyl)-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate
CFAMM00525512 CHEMBL252838 Bioactive N-[(2R)-3-(2-chlorophenyl)-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]-1-(trifluoromethyl)cyclopropane-1-carboxamide
CFAMM00525511 CHEMBL400846 Bioactive tert-butyl N-[(2R)-3-[2-fluoro-6-(trifluoromethyl)phenyl]-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate
CFAMM00525510 CHEMBL252240 Bioactive tert-butyl N-[(2R)-3-[3-fluoro-2-(trifluoromethyl)phenyl]-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate
CFAMM00525509 CHEMBL252438 Bioactive tert-butyl N-[(2R)-3-(3-chlorophenyl)-1-oxo-1-[[3-(1-phenylcyclopropyl)imidazo[4,5-b]pyridin-2-yl]methylamino]propan-2-yl]carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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