CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45191
Family Name Beta-secretase 1 inhibitor 2-[2-(3-cyanophenyl)-5-(4-phenoxyphenyl)pyrrol-1-yl]-N-(diaminomethylidene)acetamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00525538 Functional Category Bioactive
Superfamily Beta-secretase 1 Binder Superfamily 10
Class Class 3729

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2


External ID

Functional Category

Molecule Name

CFAMM00525538 CHEMBL398316 Bioactive 2-[2-(3-cyanophenyl)-5-(4-phenoxyphenyl)pyrrol-1-yl]-N-(diaminomethylidene)acetamide
CFAMM00525537 CHEMBL254057 Bioactive N-(diaminomethylidene)-2-[2-(4-methoxyphenyl)-5-(4-phenoxyphenyl)pyrrol-1-yl]acetamide
CFAMM00525536 CHEMBL400087 Bioactive 2-[2-[4-(4-acetylphenoxy)phenyl]-5-(3-cyanophenyl)pyrrol-1-yl]-N-(diaminomethylidene)acetamide
CFAMM00525535 CHEMBL399083 Bioactive N-(diaminomethylidene)-2-[2-(4-phenoxyphenyl)-5-[4-(trifluoromethyl)phenyl]pyrrol-1-yl]acetamide
CFAMM00525539 CHEMBL401172 Bioactive AGN-PC-00E6XR

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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