CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM452
Family Name Serine/threonine-protein kinase B-raf inhibitor SureCN1013580 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00311700 Functional Category Bioactive
Superfamily B-lymphocyte antigen CD20 Inhibitor Iodine-131-tositumomab Superfamily
Class Class 795

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tyrosine kinase Inhibitor PKI166 Family 17 198
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YMN ... 7 11
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YXQ ... 2 1
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 3 0
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase inhibitor SureCN... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 12 2
Tyrosine-protein kinase JAK2 inhibitor (2R)-2-[4-[[8-(4-methox... 2 0
Hepatocyte growth factor receptor ligand 6-[(1S)-1-[6-(2,3-dih... 1 5
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-07CQG5 ... 2 1
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311700 CHEMBL1080931 Bioactive SureCN1013580
CFAMM00311699 CHEMBL1088438 Bioactive SureCN1016555

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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