CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45334
Family Name Multidrug resistance-associated protein 1 and Multidrug resistance protein 1B inhibitor 4-[4-[2-(4-nitrophenyl)ethyl]piperazin-1-yl]-6,7,8,9-tetrahydropyrimido[4,5-b]indolizine-10-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00525851 Functional Category Bioactive
Superfamily Aromatase and Rho-associated protein kinase 1 Binder Superfamily
Class Class 2100

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Aromatase Inhibitor NSC-356781 Family 3 10
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16


External ID

Functional Category

Molecule Name

CFAMM00525851 CHEMBL27171 Bioactive 4-[4-[2-(4-nitrophenyl)ethyl]piperazin-1-yl]-6,7,8,9-tetrahydropyrimido[4,5-b]indolizine-10-carbonitrile
CFAMM00525850 CHEMBL27172 Bioactive SureCN6921744

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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