CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4548
Family Name Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand CHEMBL1418913 family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00357317 Functional Category Bioactive with Natural Product
Superfamily Prolyl endopeptidase Inhibitor Y-29794 Superfamily
Class Class 2958

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 2 14
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 10
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
5-hydroxytryptamine receptor 6 ligand 2-methyl-5-methylsulfany... 1 1
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 2 0
Mitogen-activated protein kinase kinase kinase 11 and Mitogen-... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL246396 family 22 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL3... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00357314 CHEMBL144084 Bioactive SureCN4998477

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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