CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45494
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor (3E)-3-[[3-(3-bicyclo[2.2.1]heptanyloxy)-4-methoxyphenyl]methylidene]-1H-indol-2-one family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00526180 Functional Category Bioactive with Natural Product
Superfamily Melanin-concentrating hormone receptor 1 and Cyclic AMP-specific phosphodiesterase SSPDE4A1A Binder Superfamily
Class Class 2065

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
MO15-related protein kinase Pfmrk Inhibitor 3-[3-(2-hydroxy-et... 1 6
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
D(2) dopamine receptor Ligand Epidepride Family 31 66
Transient receptor potential cation channel subfamily V member... 1 5
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 12
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Cyclic AMP-specific phosphodiesterase SSPDE4A1A inhibitor AGN-... 2 8
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 0
Cyclic AMP-specific phosphodiesterase SSPDE4A1A inhibitor Sure... 1 0
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526180 CHEMBL291838 Bioactive (3E)-3-[[3-(3-bicyclo[2.2.1]heptanyloxy)-4-methoxyphenyl]methylidene]-1H-indol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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