CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45585
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 3-[4-[[3-[(4-nitrophenyl)methyl]imidazol-4-yl]methylamino]-2-phenylphenyl]benzoic acid family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00526377 Functional Category Bioactive
Superfamily Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor TAK-700 Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Eluxadoline family 4 85
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526378 CHEMBL55427 Bioactive SureCN12519094
CFAMM00526377 CHEMBL55484 Bioactive 3-[4-[[3-[(4-nitrophenyl)methyl]imidazol-4-yl]methylamino]-2-phenylphenyl]benzoic acid
CFAMM00526376 CHEMBL299245 Bioactive methyl 3-[4-[[3-[(4-nitrophenyl)methyl]imidazol-4-yl]methylamino]-2-phenylphenyl]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27161 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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