CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45608
Family Name Neuromedin-K receptor ligand AGN-PC-00GCXP family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00526425 Functional Category Bioactive with Natural Product
Superfamily Neuromedin-K receptor Ligand SB222200 Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
Neuromedin-K receptor Ligand SB222200 Family 17 235
Reverse transcriptase Inhibitor IDX899 Family 2 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Setipiprant family 5 118
CP-18770 family 6 27
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Endothelin B receptor Ligand IRL-2500 Family 34 87
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Mitogen-activated protein kinase 1 and Nonstructural protein 1... 1 33
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Hematopoietic prostaglandin D synthase inhibitor 4-(3-methylis... 1 7
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16b ... 2 0
Neuromedin-K receptor and Potassium voltage-gated channel subf... 13 2
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Histone deacetylase 1 inhibitor (2S)-N'-hydroxy-2-(pyridine-2-... 3 0
Glycogen phosphorylase, liver form inhibitor 2-[(1R,2R)-2-[(5-... 3 2
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 3


External ID

Functional Category

Molecule Name

CFAMM00526424 CHEMBL54205 Bioactive SureCN6448631
CFAMM00526426 CHEMBL301278 Bioactive SureCN13957927
CFAMM00526425 CHEMBL50571 Bioactive AGN-PC-00GCXP

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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