CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45626
Family Name Pol polyprotein inhibitor N-[(2S,3R,4R,5R)-1-cyclohexyl-3,4-dihydroxy-5-[[(1R,2S)-1-hydroxy-2,3-dihydro-1H-inden-2-yl]carbamoyl]-6-methylheptan-2-yl]-2-(phenylsulfanylmethoxy)benzamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00526470 Functional Category Bioactive
Superfamily Pol polyprotein and Beta-1 adrenergic receptor Binder Superfamily
Class Class 322

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526470 CHEMBL302516 Bioactive N-[(2S,3R,4R,5R)-1-cyclohexyl-3,4-dihydroxy-5-[[(1R,2S)-1-hydroxy-2,3-dihydro-1H-inden-2-yl]carbamoyl]-6-methylheptan-2-yl]-2-(phenylsulfanylmethoxy)benzamide
CFAMM00526472 CHEMBL71396 Bioactive N-[(2S,3R,4R,5R)-1-cyclohexyl-3,4-dihydroxy-5-[[(1R,2S)-1-hydroxy-2,3-dihydro-1H-inden-2-yl]carbamoyl]-6-methylheptan-2-yl]-2-(phenoxymethoxy)benzamide
CFAMM00526471 CHEMBL366531 Bioactive N-[(3R,4R,5R)-1-cyclohexyl-3,4-dihydroxy-5-[[(1S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-6-methylheptan-2-yl]-2-(phenylsulfanylmethoxy)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543