CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45648
Family Name Arachidonate 5-lipoxygenase inhibitor 5-(1,3-benzodioxol-5-yl)furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-6,8-dione family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00526534 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 Inhibitor Hinokinin Superfamily
Class Class 605

Cousin Family NamesSeedsMembers
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Endothelin-1 receptor Ligand PD156707 Family 41 211
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Cytochrome P450 3A4 Inhibitor Hinokinin Family 2 10
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Prostaglandin G/H synthase 2 Inhibitor Neolignan 9-nor-7,8-deh... 1 7
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Acetylcholinesterase inhibitor AGN-PC-003A5N family 3 9
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Arachidonate 5-lipoxygenase inhibitor AGN-PC-00PO2W family 1 1
Putative NP ZINC02398203 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526530 CHEMBL66095 Bioactive AGN-PC-074DBB
CFAMM00526534 CHEMBL304018 Bioactive 5-(1,3-benzodioxol-5-yl)furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-6,8-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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