CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45702
Family Name Caspase-1 inhibitor (3S)-3-[2-[6-benzyl-2-oxo-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoylamino]-4-oxobutanoic acid family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00526644 Functional Category Bioactive
Superfamily Angiotensin-converting enzyme and Caspase-1 Binder Superfamily
Class Class 506

Cousin Family NamesSeedsMembers
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-4-[(3-oxo-3-phen... 1 1


External ID

Functional Category

Molecule Name

CFAMM00526646 CHEMBL308921 Bioactive (3S)-3-[[2-[6-butyl-2-oxo-3-(3-phenylpropanoylamino)pyridin-1-yl]acetyl]amino]-4-oxobutanoic acid
CFAMM00526645 CHEMBL71025 Bioactive (3S)-3-[[2-[6-benzyl-2-oxo-3-(3-phenylpropanoylamino)pyridin-1-yl]acetyl]amino]-4-oxobutanoic acid
CFAMM00526644 CHEMBL69576 Bioactive (3S)-3-[2-[6-benzyl-2-oxo-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoylamino]-4-oxobutanoic acid
CFAMM00526643 CHEMBL308700 Bioactive (3S)-4-oxo-3-[[(2S)-2-[2-oxo-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoyl]amino]butanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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