CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45747
Family Name Reverse transcriptase/RNaseH inhibitor Thiazoloisoindol-5-one deriv. 70 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00526735 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Peptide deformylase Binder Superfamily
Class Class 295

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Endothelin B receptor Ligand IRL-2500 Family 34 87
Substance-K receptor ligand 1-N,2-N-bis[2-(1H-indol-3-yl)ethyl... 1 0
Survival motor neuron protein and Menin inhibitor CHEMBL151109... 1 11
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... 11 0
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... 2 1
Platelet-activating factor receptor ligand 52770 RP family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526735 CHEMBL313273 Bioactive Thiazoloisoindol-5-one deriv. 70

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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