CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45776
Family Name Reverse transcriptase/RNaseH inhibitor Thiazoloisoindol-5-one deriv. 14 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00526794 Functional Category Bioactive with Natural Product
Superfamily Matrix metalloproteinase-9 and Nuclear receptor ROR-gamma Binder Superfamily
Class Class 3308

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Beta-lactamase and Histone-lysine N-methyltransferase 2A inhib... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526794 CHEMBL316151 Bioactive Thiazoloisoindol-5-one deriv. 14

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26380 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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