CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45796
Family Name Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00526829 Functional Category Bioactive
Superfamily Fatty-acid amide hydrolase 1 Inhibitor Btnp Superfamily
Class Class 2917

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
DNA topoisomerase 2-beta Inhibitor Salvicine Family 2 9
CPI-613 family 4 35
Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Family 2 86
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a... 2 23
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
Chymotrypsinogen B inhibitor (6E)-6-(iodomethylidene)-4-phenyl... 1 1
Aldo-keto reductase family 1 member C3 inhibitor (8R,9S,13S,14... 2 0
Peroxisome proliferator-activated receptor gamma ligand SureCN... 3 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Metabotropic glutamate receptor 1 ligand SureCN186260 family 1 4
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Putative NP ZINC35464636 Family 6 1
Putative NP ZINC14410655 Family 6 4
Putative NP ZINC06763537 Family 6 4
NP 3,3,5,5-tetramethyl-6-(phenylethynyl)dihydro-2h-pyran-2,4(3... 6 3
7a-hydroxy-7-phenyl-3,3a,4,5,6,7-hexahydro-1-benzofuran-2-one ... 4 0
Putative NP ZINC02930279 Family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526829 CHEMBL318592 Bioactive AGN-PC-074TA8
CFAMM00526834 CHEMBL327963 Bioactive SureCN6762870

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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