CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45805
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor AGN-PC-074WKZ family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00526850 Functional Category Bioactive
Superfamily Thromboxane-A synthase and Platelet-activating factor receptor Binder Superfamily
Class Class 2472

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Alpha-1A adrenergic receptor Ligand A-131701 Family 16 17
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 14
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00526850 CHEMBL320296 Bioactive AGN-PC-074WKZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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