CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45915
Family Name Glutamate carboxypeptidase 2 inhibitor 2-[(3-hydroxyphenyl)methyl]-3-phosphonopropanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00527033 Functional Category Bioactive
Superfamily Glutamate carboxypeptidase 2 inhibitor 2-[(3-hydroxyphenyl)methyl]-3-phosphonopropanoic acid Superfamily
Class Class 2550

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor ligand L-Tyrosine derivative Methyld... 2 3
Tyrosine 3-monooxygenase Inhibitor L-tyrosine Family 4 36
Oestrogen receptor ligand Dienestrol Family 35 440
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Epidermal growth factor receptor Ligand AG-538 Family 5 11
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Aromatase inhibitor (3R,4R)-4-benzyl-3-[(3-hydroxyphenyl)methy... 1 10
G2/mitotic-specific cyclin-B1 and Cyclin-dependent kinase 1 in... 2 8
Putative NP ZINC03197541 Family 1 0
2,4-bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylate NP ZINC0... 1 0


External ID

Functional Category

Molecule Name

CFAMM00527033 CHEMBL334532 Bioactive 2-[(3-hydroxyphenyl)methyl]-3-phosphonopropanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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