CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM45995
Family Name Thromboxane A2 receptor ligand (Z)-7-[(4S,5R)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]hept-5-enoic acid family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00527166 Functional Category Bioactive
Superfamily Thromboxane A2 receptor ligand (Z)-7-[(4S,5R)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]hept-5-enoic acid Superfamily
Class Class 606

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Thromboxane A2 receptor and Cytochrome P450 3A4 ligand Tocris-... 1 1
Thromboxane A2 receptor ligand (Z)-7-[3-[(E,3R,4S)-3-hydroxy-4... 1 7
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R)... 1 9
Thromboxane A2 receptor ligand (Z)-6-[(2S,4S,5R)-2-(4-cyanophe... 1 0
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Sigma non-opioid intracellular receptor 1 ligand 3-[(2S,4R)-2-... 3 5
Sodium-dependent dopamine transporter inhibitor SureCN4384348 ... 1 3
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Acetals Metabolite 1-Benzyloxy-1-(2-methoxyethoxy)ethane Family 3 50
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
Toluenes Metabolite Tolualdehyde glyceryl acetal Family 3 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00527158 CHEMBL349706 Bioactive (Z)-7-[(4S,5R)-4-phenyl-1,3-dioxan-5-yl]hept-5-enoic acid
CFAMM00527166 CHEMBL345614 Bioactive (Z)-7-[(4S,5R)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]hept-5-enoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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