CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor AGN-PC-03WEFP family
No. of Seeds 8 No. of Other Members 8
Family Centroid CFAMM00101465 Functional Category Bioactive
Superfamily Mu-type opioid receptor Ligand Anileridine Superfamily
Class Class 581

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Mu-type opioid receptor Ligand Anileridine Family 3 18
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Type-1 angiotensin II receptor Ligand RTI-76 Family 3 6
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 11 20
D(4) dopamine receptor and D(2) dopamine receptor ligand methy... 2 11
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 5
Sodium-dependent dopamine transporter inhibitor methyl (2R)-2-... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 7 2
Sodium-dependent dopamine transporter inhibitor 2-(4-aminophen... 5 0
Sodium-dependent dopamine transporter inhibitor methyl (1R,3S)... 1 0
Sodium-dependent dopamine transporter inhibitor 2-[4-[(2-bromo... 1 0
Sodium-dependent dopamine transporter inhibitor methyl (1R,3S)... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00306266 CHEMBL2310852 Bioactive methyl (1R,3S,4S)-3-(4-azidophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00306271 CHEMBL606936 Bioactive methyl (1R,3S)-3-(4-amino-3-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00306277 CHEMBL100625 Bioactive AGN-PC-074P8R
CFAMM00306268 CHEMBL607198 Bioactive methyl (1R,3S,4S)-3-(4-aminophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00306274 CHEMBL607148 Bioactive methyl (1R,3S,4S)-3-(4-azido-3-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00306267 CHEMBL607197 Bioactive methyl (1R,3S,4S)-3-(4-amino-3-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543