CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46019
Family Name Tyrosine-protein kinase Lck and Tyrosine-protein kinase Fyn inhibitor 2-Bromo-4,5-dimethoxybenzoic acid family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00527213 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lck and Tyrosine-protein kinase Fyn inhibitor 2-Bromo-4,5-dimethoxybenzoic acid Superfamily
Class Class 6765

Cousin Family NamesSeedsMembers
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
taste receptor Ligand Cynarin Family 6 124
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Endothelin-1 receptor Ligand PD156707 Family 41 211
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Isocitrate lyase Inhibitor Bis(3-bromo-4,5-dihydroxyphenyl)met... 1 2
Tyrosine-protein kinase Lck inhibitor 2-[(3,5-dibromo-4-hydrox... 3 1


External ID

Functional Category

Molecule Name

CFAMM00527213 CHEMBL349371 Bioactive 2-Bromo-4,5-dimethoxybenzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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