CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4611
Family Name Mitogen-activated protein kinase 13 and Mitogen-activated protein kinase 12 inhibitor AGN-PC-03T1YH family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00357725 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 3679

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand Napht... 5 14
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Corticotropin-releasing factor receptor 1 ligand 8-[butyl(ethy... 2 6
Corticotropin-releasing factor receptor 1 ligand 3-chloro-4-[8... 7 1
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 15 0
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762YG family 2 2
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 5 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Non-receptor tyrosine-protein kinase TYK2 ligand SureCN1298914... 3 0
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 7 7
C-X-C chemokine receptor type 3 ligand 1-[3-[[(1R,5S)-3-[[7-(t... 3 1
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 3 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 6-(2-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00357726 CHEMBL357598 Bioactive SureCN6667987
CFAMM00357725 CHEMBL142463 Bioactive AGN-PC-03T1YH
CFAMM00357723 CHEMBL358108 Bioactive AGN-PC-075PEJ
CFAMM00357729 CHEMBL343682 Bioactive AGN-PC-044QXP
CFAMM00357728 CHEMBL142697 Bioactive AGN-PC-044QZH

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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