CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4614
Family Name Inositol monophosphatase 1 and Microtubule-associated protein tau inhibitor CHEMBL1424953 family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00357749 Functional Category Bioactive
Superfamily Beta-lactamase and Retinal dehydrogenase 1 Binder Superfamily
Class Class 3101

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Aurora kinase A and Aurora kinase B Inhibitor Amg 900 Family 1 1
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 4
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 8
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Vascular endothelial growth factor receptor 2 ligand ST5005116... 1 11
Epidermal growth factor receptor and Mitogen-activated protein... 5 19
Dual specificity protein kinase CLK4 and Dual specificity tyro... 1 14
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 2
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 11 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 2
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Serine/threonine-protein kinase B-raf inhibitor 1-[3-(4-amino-... 1 1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 7 7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 2 0
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 4 24
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 0
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2... 1 8
Cysteinyl leukotriene receptor 1 and Platelet-activating facto... 1 1
Epidermal growth factor receptor ligand AGN-PC-07C0GB family 1 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00357746 CHEMBL2377091 Bioactive AGN-PC-07AYTA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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