CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46141
Family Name Integrase and Serine/threonine-protein kinase pim-1 inhibitor FZ41 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00527433 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase pim-1 and Integrase Binder Superfamily
Class Class 836

Cousin Family NamesSeedsMembers
Neuromedin-K receptor Ligand Talnetant Family 3 49
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Integrase inhibitor AC1LARQ6 family 1 2
Serine/threonine-protein kinase pim-1 and Dual specificity tyr... 2 0
2-en-1-one NP (e)-3-(benzo[d][1,3]dioxol-5-yl)-1-(6-bromo-2-me... 3 0


External ID

Functional Category

Molecule Name

CFAMM00527435 CHEMBL37139 Bioactive 8-hydroxy-2-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]quinoline-7-carboxylic acid
CFAMM00527434 CHEMBL83746 Bioactive AC1NX3S7
CFAMM00527433 CHEMBL36640 Bioactive FZ41

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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