CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46201
Family Name RAF proto-oncogene serine/threonine-protein kinase inhibitor 3-[(E)-2-(2,6-dimethyl-4-pyridin-3-ylphenyl)ethenyl]-5-(2H-tetrazol-5-yl)pyridine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00527518 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily 11
Class Class 1331

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00527518 CHEMBL374647 Bioactive 3-[(E)-2-(2,6-dimethyl-4-pyridin-3-ylphenyl)ethenyl]-5-(2H-tetrazol-5-yl)pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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