CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46252
Family Name Estrogen receptor beta and Estrogen receptor ligand 8-amino-3-hydroxy-4,7-dimethylbenzo[c]chromen-6-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00527589 Functional Category Bioactive with Natural Product
Superfamily Estrogen receptor and Cytochrome P450 3A4 Binder Superfamily 2
Class Class 1873

Cousin Family NamesSeedsMembers
Aldose reductase Inhibitor 7-hydroxy-6-nitro-2-phenyl-chromen-... 2 17
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Nuclear receptor ROR-gamma and Retinal dehydrogenase 1 ligand ... 1 8


External ID

Functional Category

Molecule Name

CFAMM00527588 CHEMBL383753 Bioactive N-(3-hydroxy-4,7-dimethyl-6-oxobenzo[c]chromen-8-yl)methanesulfonamide
CFAMM00527589 CHEMBL380844 Bioactive 8-amino-3-hydroxy-4,7-dimethylbenzo[c]chromen-6-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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