CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM46264
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 2 and Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureCN681900 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00527610 Functional Category Bioactive
Superfamily Heat shock protein 90, putative Inhibitor Cromoglicate Superfamily
Class Class 197

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Ipriflavone family 62 2480
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Integrase Inhibitor L-708,906 Family 1 8
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Peroxisome proliferator-activated receptor delta ligand SureCN... 1 0
Androgen receptor and Estrogen receptor ligand estradiol benzo... 1 29
Protein kinase C beta type and Protein kinase C eta type inhib... 1 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7
Glutamate carboxypeptidase 2 inhibitor 2-phenylmethoxy-6-(2-su... 2 3
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00527610 CHEMBL382614 Bioactive SureCN681900

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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